The improve of Aids research

At present, for most of the world, the only practical means of control is by minimizing transmission. This requires education programs to promote the use of condoms as well as discouraging sexual promiscuity. Also, getting quarterly and habit Std check-ups at Std clinics can help forestall the spread. In high-income countries, the availability of medication has made Hiv infection no longer a safe bet death sentence. Unfortunately, improvements in managing Hiv infection have resulted in a relaxed attitude toward safe sex practices.

The fact tends to be overlooked that the available drugs only delay the progress of the infection, they are not a cure. Attempts to forestall the use of contaminated needles among Iuds are also important. To be effective, educational programs often wish fundamental group changes that are not easy to accomplish, but they have slowed the infection rate in some areas. The fast mutation pace of Hiv makes it hard to generate a vaccine that is sufficient against all forms of the virus. an additional one obstacle is the range of routes by which Hiv can be transmitted. An sufficient vaccine would have to defend against transmission via diverse mucosal routes that is proving to be the intangible goal in tests with simian immunodeficiency virus that have been performed in monkeys.

Hiv Antiretroviral Drugs

Some experts believe that no Hiv vaccine is potential that will confer nearly perfect protection, such as those for smallpox or measles. It is opinion that a more practical goal may be to develop a vaccine that will stimulate cell-mediated immunity in already infected persons and help the patient's immune system to clear the virus. Much progress has been made in the use of chemotherapy to inhibit Hiv infections. To reproduce, the virus makes use if safe bet protease enzymes that cut proteins into pieces, which are then re-assembled into the coat of new Hiv particles. Drugs called protease inhibitors inhibit this enzyme and are now in use.

Because of the increasing estimate of drugs that control reproduction of the virus, at least temporarily, Hiv infection is approximately at the stage where it can be carefully a treatable persisting disease, assuming that the treatment is affordable. The rapid reproductive rate and frequent occurrence of drug-resistance mutations dictates that many drugs, given simultaneously, must be used. The highly active antiretroviral therapy (Haart) is a therapy consisting of administering drug combinations. Patients are often required to take as many as 40 pills per day on a involved schedule, which must be adhered to rigorously because the virus is unforgiving. Even so, unyielding strains of the virus are likely to emerge.

The Aids epidemic gives clear evidence of the value of basic scientific Aids research. Without the advances in molecular biology of the past few decades, we would have been unable even to identify the causative agent of Aids. We would not have been able to develop the tests for screening donated blood, to identify points in the viral life cycle for which selectively toxic drugs could be developed, or even monitor the policy of the infection. In the lifetime of most of us, we will have the opportunity to survey healing history being made as the struggle with this deadly and elusive virus continues.

The improve of Aids research

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